From Hwy-191 Westbound: West on Hwy-191 to intersection of 42nd and Andrews Hwy. Ector County Coliseum is located on the northwest corner of intersection. From I-20: I-20 to Hwy-385, exit 116 (Odessa). North on Hwy-385 (through Odessa) to intersection of 42nd and Andrews Hwy. Coliseum is on the northwest corner.