From the North (Charlotte): I-85 South to I-385 North (towards downtown Greenville). Follow I-385 for approximately 6.5 miles and watch for arena on the right. From the South (Atlanta): I-85 North to 185 toward Greenville. 185 turns into Mills Avenue and then becomes Church Street which brings you into Downtown Greenville. Arena is on the right. From the East (Columbia): I-26 West to I-385 North (towards Greenville). Follow I-385 into downtown Greenville and watch for arena on the right (approx. 6.5 miles from I-85). From the West (Knoxville): I-40 East to I-26 East to I-85 South. Take I-85 South to I-385 North (towards downtown Greenville). Follow I-385 for approx. 6.5 miles and watch for arena on the right. From the Northwest (Asheville): I-26 East to I-85 South. Take I-85 South to I-385 North (towards downtown Greenville). Follow I-385 for approx. 6.5 miles and watch for arena on the right.